Kate and Humphrey and their 3 wolf cubs, Stinky, Claudette and Runt, are happily preparing to celebrate their first winter holidays together when their smallest cub, Runt, mysteriously disappears. They must now go on a new journey across the wilderness to find and bring back Runt before the winter festivities begin at home. It's their greatest adventure yet, filled with both action and suspense as well as plenty of the humor and heartwarming moments that was delivered in the first theatrical release. While their adventure does not end exactly as planned, in the end Kate and Humphrey must make new holiday plans, but discover that "Home is where the Family is".