James Cagney and Joan Blondell star as a wanna-be con man and the girl who can drive any man Blonde Crazy. Conniving bellhop Bert Harris (Academy Award winner Cagney) uses Ann Roberts (Blondell) as a lure to scam a jewelry salesman (Guy Kibbee) out of $5,000, and the pair head to New York City. But this small-time swindler in the Big Apple is soon scammed out of his cash. And Roberts realizes she can work alone by conning straight-arrow Joe Reynolds (Academy Award winner Ray Milland) into marriage--and a permanent meal ticket. When Harris turns to real crime to get the money to win Roberts back--and Roberts realizes she can't lead a life as a respectable wife--he lands in prison, and she vows to wait for him in this pre-Hayes Code comic romance.