In a terrifying tale of the "American Dream" gone horribly wrong, residents of a picture-perfect Midwestern town begin to succumb to an uncontrollable urge for violence when a mysterious toxin in the water supply turns everyone exposed to it into mindless killers. Sheriff David Dutton (Timothy Olyphant); his pregnant wife, Judy (Radha Mitchell); Becca (Danielle Panabaker), an assistant at the medical center; and Russell (Joe Anderson), Dutton’s deputy and right-hand man, find themselves trapped in a once idyllic town they can no longer recognize. Unable to trust former neighbors and friends, deserted by the authorities and terrified of contracting the illness themselves, they are forced to band together in a nightmarish struggle for survival in this reinvention of the George Romero classic.